Declining sponsored research funding has caused many medical schools to re-evaluate their fixed costs, especially space costs, associated with research. The AAB Cardiovascular Research Institute moved off campus 8 years ago to expand its space and occupy a former commercial research building about 10 minutes from the main campus. In 2015, space was made available in one of the newest research buildings on the main campus to accommodate the CVRI and release the off campus lab building for clinical uses, thus saving the facility costs. Additionally, collaboration and access to shared resources was possible again. This project was completed in collaboration with Jacobs Consultancy.